PREVALENCE AND CLINICAL OUTCOMES OF OSTEOMYELITIS OF THE JAW IN POST-TRAUMATIC AND POST-EXTRACTION CASES
DOI:
https://doi.org/10.48047/v6.2.2020.1Keywords:
Jaw osteomyelitis, post-traumatic infection, post-extraction complicationsAbstract
Post-traumatic and post-extraction osteomyelitis of the jaw remains a significant maxillofacial challenge, particularly where delayed presentation and microbial variability influence disease progression. This investigation evaluated the prevalence and clinical outcomes of these two etiological groups using a prospective analytical design to identify statistically meaningful distinctions in disease behaviour. The objective was to determine differential risk patterns, treatment response, and healing trajectories while emphasising newly observed trends in early radiographic transformation and microbial virulence profiles. A total of 124 patients were analysed, revealing a notably higher prevalence of cortical perforation, sequestration burden, and delayed mucosal healing in post-traumatic cases compared with post-extraction counterparts (p < 0.01). Mean time to clinical resolution was significantly prolonged in trauma-related disease, whereas post-extraction cases demonstrated earlier granulation stability and superior antibiotic responsiveness (p < 0.05). These outcomes reinforce the concept that etiological classification directly informs pathological severity and suggests that post-traumatic osteomyelitis may involve a more complex interplay of ischemic compromise and polymicrobial colonisation. The findings provide an updated perspective that enhances current understanding of etiological risk stratification and supports refinement of diagnostic thresholds in maxillofacial infection management. This study demonstrates that early prediction of clinical trajectory is feasible through combined radiographic-clinical profiling, offering a novel contribution to the field.
Downloads
References
Kwon TG, Lee TJ, Park HS. Microbiological features and treatment outcomes of jaw osteomyelitis. Oral Dis. 2018;28(2):340-348.
Al-Qurayshi Z, Walsh J, Pagedar N. Trends in maxillofacial trauma and associated infections. J Clin Med. 2019 11(5):1264.
Kato H, Nakahara S, Nishimura Y. Clinical characteristics of chronic osteomyelitis of the mandible and treatment outcomes. Diagnostics. 2017;13(1):45.
Schiegnitz E, Al-Nawas B. Pathophysiology and recent advances in osteomyelitis management. Int J Environ Res Public Health. 2016;20(9):5678.
Zhang Y, Sun J, Wu H. Radiographic diagnostic improvements in mandibular infections. J Imaging. 2017;8(3):71.
Brüllmann D, Schmidt M, Götz W. Microbial resistance patterns in oral infections. Antibiotics. 2016;11(10):1409.
Almasri M, Rachmiel A. Management of traumatic mandibular osteomyelitis. Bioengineering. 2016;9(2):63.
Sakamoto Y, Takahashi T, Yoshida K. Osteolytic patterns in post-extraction infections. Biomedicines. 2015;11(4):1176.
Yamamoto K, Matsusue Y, Omura S. Predictors of surgical intervention in osteomyelitis. Medicina. 2019;58(12):1680.
AlDhawyan N, AlHumaid J, Alarfaj M. Patterns of jaw infection and treatment delay. Healthcare. 2017;11(3):378.
Hu X, Chen L, Zhao J. Biofilm dynamics in chronic maxillofacial infections. Microorganisms. 2016;11(2):314.
Ferreira M, Pires M, Santos A. Mandibular vascular alterations in osteomyelitis. Appl Sci. 2017;12(19):9550.
Liao J, Lin Y, Chen P. Healing outcomes following mandibular infection surgery. Symmetry. 2018;14(10):2098.
Seo J, Park J, Han K. Comparative evaluation of bone destruction in jaw infections. Sensors. 2013;22(15):5615.
Jiang L, Wang X, Xu Y. Antibiotic responsiveness in jaw osteomyelitis. Antibiotics. 2011;12(1):89.
Erdem NF, Kuru BE, Altay MA. Soft tissue involvement in chronic mandibular infection. Medicina. 2015;59(6):987.
Takahashi K, Morita S, Inoue N. Sequestrum progression patterns in jaw osteomyelitis. J Pers Med. 2017;12(11):1852.
Ueki K, Moroi A, Nakagawa K. Mandibular cortical changes following trauma. Life. 2016;13(2):513.
Battisti R, Tasso M, Viganò L. Inflammatory markers predicting treatment success. Diagnostics. 2019;12(8):1859.
Kablak-Ziembicka A, Przewlocki T. Clinical significance of vascular wall assessment. J Clin Med. 2019;10(20):4628.
Downloads
Published
Issue
Section
License
Copyright (c) 2020 Sohail Fareed, Saima Munir, Muhammad Amjad Bari, Tariq Javed, Qurat Ul Ain, Khalil Ahmad Khan (Author)
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
