Development of In -Situ Gel For Ocular Drug Delivery
DOI:
https://doi.org/10.48047/Keywords:
In-situ gel, Ocular drug delivery, Poloxamer, Carbomer, Gellan gumAbstract
Background: Conventional ophthalmic solutions suffer from poor bioavailability due to rapid precorneal drainage, necessitating frequent administration and potentially causing patient non compliance. In-situ gelling systems offer a promising approach by transforming from solution to gel upon ocular administration, thereby prolonging drug residence time
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References
Slater, J. The Effects of Co-Solvent Levels and Neutralisation on the Rheology of Carbopol Gels. In Third European Rheology Conference and Golden Jubilee Meeting of the British Society of Rheology; Oliver, D.R., Ed.; Springer: Dordrecht, The Netherlands, 1990; pp. 453–455. [Google Scholar]
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