Preparation and Evaluation of Nanoparticle-Based Drug Delivery System for the Management of Atherosclerosis using Atorvastatin

Authors

  • Sri Pavan Chowdary Nekkanti, Kranthi, Praveen Guijula, D. Raghava, Kavala Nageswara Rao Author

DOI:

https://doi.org/10.48047/

Keywords:

Atherosclerosis, Atorvastatin, PLGA nanoparticles, Drug delivery system, Macrophage targeting

Abstract

Atherosclerosis remains the leading cause of cardiovascular morbidity and mortality worldwide, with conventional therapeutic approaches facing significant limitations including poor drug bioavailability at plaque sites and systemic adverse effects. This research aimed to develop and  evaluate atorvastatin-loaded poly(lactic-co-glycolic

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References

Negre-Salvayre, A.; Guerby, P.; Gayral, S.; Laffargue, M.; Salvayre, R. Role of reactive oxygen species in atherosclerosis: Lessons from murine genetic models. Free Radic. Biol. Med. 2020, 149, 8–22.

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Published

2026-04-26

Issue

Vol. 12 No. 1 (2026): 12 (1) 2026

Section

Articles

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How to Cite

Sri Pavan Chowdary Nekkanti, Kranthi, Praveen Guijula, D. Raghava, Kavala Nageswara Rao. (2026). Preparation and Evaluation of Nanoparticle-Based Drug Delivery System for the Management of Atherosclerosis using Atorvastatin . History of Medicine, 12(1), 173-184. https://doi.org/10.48047/