Study of Detection of Human Rotavirus in Stool Specimen by ELISA Technique and Association of Enteric Pathogens in Childhood Diarrhoea in a Tertiary Care Hospital, Rajasthan
DOI:
https://doi.org/10.48047/Keywords:
Rotavirus; ELISA; Childhood diarrhoea; Enteric pathogens; Escherichia coli; ROTAVAC; Seasonal variation; Rajasthan; Tertiary care hospitalAbstract
Background: Rotavirus remains the single most important cause of severe acute gastroenteritis in infants and young children worldwide, responsible for an estimated 128,500 deaths annually in children under five years, with more than 80% occurring in South Asia and sub-Saharan Africa. Despite the introduction of the indigenous oral vaccine ROTAVAC into India's Universal Immunization Programme in 2016, region-specific surveillance data from Rajasthan remain scarce. This study was undertaken to detect humanrotavirus in stool specimens by ELISA and to evaluate its association with other enteric pathogens in children with acute diarrhoea at a tertiary care hospital in Rajasthan.
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References
World Health Organization. Diarrhoeal disease. WHO Fact Sheets. Geneva: WHO; 2021.
UNICEF, World Health Organization. Diarrhoea: Why Children Are Still Dying and What Can Be Done. Geneva: WHO Press; 2009.
Bhan MK. Accelerated progress to reduce under-5 mortality in India. Lancet Glob Health. 2013;1(4):e172 e173.
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