Development of Liposomal Drug Delivery System for Doxorubicin Hydrochloride
DOI:
https://doi.org/10.48047/Keywords:
Liposomes, Anticancer drugs, Drug delivery systems, Targeted therapy, NanomedicineAbstract
Cancer remains a global health challenge with conventional chemotherapy limited by poor drug solubility, non-specific biodistribution, systemic toxicity, and multidrug resistance. Liposomal drug delivery systems have emerged as a promising solution, offering biocompatibility, versatility in drug encapsulation, and the ability to target tumor tissues selectively.
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References
Nsairat, H.; Khater, D.; Sayed, U.; Odeh, F.; Al Bawab, A.; Alshaer, W. Liposomes: Structure, composition, types, and clinical applications. Heliyon 2022, 8, e09394. [Google Scholar] [CrossRef]
Alshaer, W.; Zraikat, M.; Amer, A.; Nsairat, H.; Lafi, Z.; Alqudah, D.A.; Al Qadi, E.; Alsheleh, T.; Odeh, F.; Alkaraki, A.; et al. Encapsulation of echinomycin in cyclodextrin inclusion complexes into liposomes: In vitro anti-proliferative and anti-invasive activity in glioblastoma. RSC Adv. 2019, 9, 30976–30988. [Google Scholar] [CrossRef]
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